antiplatelet therapy in hemodialysis patients undergoing percutaneous coronary interventions
نویسندگان
چکیده
conclusions this investigation might contribute to delineate the best treatment options for this high risk population. evidence acquisition we reviewed current evidences on the use of antiplatelet therapy in patients with esrd/hd undergoing pci, focusing on the efficacy and safety of specific agents and their indications for detailed clinical settings. results clinical setting in hd patients is the principal determinant of the type, onset, combination and duration of the dapt. however, irrespective clinical setting, in addition to aspirin, clopidogrel is currently the most used antiplatelet agent even if no information derived from rcts are available in esrd. due to the large experience acquired in routine clinical practice, the awareness of safety is higher for clopidogrel than newer antiplatelet agents. because of lack of data, the use of prasugrel and ticagrelor is actually not recommended. however, in case of high ischemic and acceptable bleeding risk, they may be selectively used in esrd/hd. context coronary artery disease is highly prevalent among patients with end stage renal disease/hemodialysis (esrd/hd) and coronary percutaneous interventions (pci) has been increased by nearly 50% over the past decade. after pci with stent placement, guidelines recommend dual antiplatelet therapy (dapt), but no specifically tailored pharmacotherapy approach is outlined for this frail population, mostly excluded from large randomized clinical trials (rcts).
منابع مشابه
Antiplatelet Therapy in Hemodialysis Patients Undergoing Percutaneous Coronary Interventions
CONTEXT Coronary artery disease is highly prevalent among patients with end stage renal disease/hemodialysis (ESRD/HD) and coronary percutaneous interventions (PCI) has been increased by nearly 50% over the past decade. After PCI with stent placement, guidelines recommend dual antiplatelet therapy (DAPT), but no specifically tailored pharmacotherapy approach is outlined for this frail populatio...
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Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention.
Despite the proven benefits of using antiplatelet therapy in patients undergoing percutaneous coronary intervention (PCI), a number of key questions remain to be answered. In recent years, clopidogrel dosing strategies among such patients have evolved considerably, with newer approaches involving loading doses prior to PCI and increases in the time interval and loading dosage in an effort to ov...
متن کامل[Therapeutic approach in patients undergoing percutaneous coronary interventions].
While the performance of percutaneous coronary interventions remains the domain of interventional cardiologists, the management of these patients before, during, and after the procedure is in the domain of general cardiologists, internists and primary care physicians. Therefore, for optimal patient care it is crucial that all engaged physicians should understand the procedural risks, complicati...
متن کاملHaemoglobin-related mortality in patients undergoing percutaneous coronary interventions.
AIMS It has recently been proposed that anaemia is an independent risk factor for development of cardiovascular disease in the general population. The impact of anaemia on long-term survival of patients with manifest coronary heart disease (CHD) has not been assessed so far. In this study, we examined the influence of haemoglobin concentrations on the outcome after percutaneous coronary interve...
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عنوان ژورنال:
nephro-urology monthlyجلد ۷، شماره ۴، صفحات ۰-۰
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